Characteristics of Diagnosis and Treatment

The annual number of outpatient visits of the Pediatric Hematology Department is over 12,000, the department has 61 inpatient beds with 110% usage rate. And the average length of hospitalization is about 8.5 days with more than 3000 hospitalized children every year. The department implements painless (under general anesthesia) bone marrow puncture, lumbar puncture + intrathecal injection, and adopts comprehensive detection methods such as bone marrow morphology, molecular biology, chromosomes, PCR, FISH, gene sequencing, and leukemia MRD monitoring to diagnose and monitor children’s blood-related diseases. More than 90% of the hospitalized children are critically ill children who are suffering from diseases such as acute leukemia, acute aplastic anemia, hemophagocytic syndrome, severe thrombocytopenia, coagulation dysfunction, various congenital childhood hematological diseases, EBV and CMV infection-related diseases, etc.

At the same time, the optimization of the low-risk chemotherapy regimen for childhood leukemia, the improvement of the chemotherapy regimen for refractory and relapsed childhood leukemia (targeted, CAR-T and other immunotherapy), and the participation in the transplantation of children with blood diseases in the adult blood transplant center have improved the cure rate to 80% for childhood leukemia.